Alright, pull up a stool. Today: epinephrine, the dose-dependent chaos goblin. Epinephrine is what happens when one molecule decides it would like access to almost every useful adrenergic receptor. Beta one: heart rate and contractility go up. Beta two: bronchodilation and some vascular smooth-muscle relaxation. Alpha one: vasoconstriction. That is why epinephrine can be an…
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The Cool Attending. Episode 5. Epinephrine — The Dose-Dependent Chaos Goblin. Alright, pull up a stool. Today: epinephrine, the dose-dependent chaos goblin. Epinephrine is what happens when one molecule decides it would like access to almost every useful adrenergic receptor. Beta one: heart rate and contractility go up. Beta two: bronchodilation and some vascular smooth-muscle…
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Episode 4: Norepinephrine – Tone with a Little Engine The Cool Attending. Episode 4. Norepinephrine — Tone With a Little Engine. Alright, pull up a stool. Today we are doing norepinephrine: vascular tone with a little engine support. Norepinephrine is one of those drugs that becomes much easier when you stop thinking of it as…
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Example Previous studies:9/19/2026 echocardiogram shows dilated cardiomyopathy EF 25% severe global hypokinesis normal biatrial size trace mitral regurg9/26 RHC…
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The point is not to memorize perfect answers. Interviewers want to see how you think under pressure, communicate across hierarchy, respond to feedback, and protect patient safety. Use the prompts below to build concise, specific stories using the STAR framework: situation, task, action, and result. Lead with reflection. Finish with what changed. Interview preparation note…
Read moreNerve impulses travel along a nerve cell as electrical signals driven by charged minerals called electrolytes, while neurotransmitters act as chemical messengers that pass the signal from one nerve cell to the next across a small gap. [1, 2, 3] Key Electrolytes Key Neurotransmitters If you’d like, I can explain: [1] https://nigms.nih.gov [2] https://bio.libretexts.org [3]…
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Vasopressors increase blood pressure by activating G protein-coupled receptors (GPCRs) on vascular smooth muscle and cardiac cells. The result is an increase in systemic vascular resistance (SVR), cardiac output (CO), or both, which raises mean arterial pressure (MAP). The signaling pathway is easiest to understand in four steps: Step 1: Vasopressor binds to a cell…
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The 4 Early Signs of Septic Shock TemperatureTachycardiaTachypneaCount of WBCs…
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